Study Links Ibuprofen With Male Infertility

10 January, 2018, 01:23 | Author: Leticia Riley
  • Ibuprofen Might Cause Male Infertility Study Shows			 0					By		Denis Bedoya

However, Kristensen emphasises that despite the results of the study, men should not stop taking the drug. But a new study raises questions about the risks of frequent usage of ibuprofen by young men.

The study looked at a small group of men - only 31 - ages 18-35 over six weeks. After 14 days of ibuprofen use, the researchers observed higher blood levels of luteinizing hormone, which regulates the production of testosterone and other hormones. The remaining 17 volunteers were given a placebo.

A study published Monday in Proceedings of the National Academy of Sciences found that regular ibuprofen use may lead to compensated hypogonadism, a condition that can lead to infertility, erectile dysfunction, depression and loss of bone and muscle mass, among other symptoms.

Before now, he says, "most warnings regarding this family of painkillers have focused on limiting long-term use in the elderly to prevent gastrointestinal, renal and cardiac adverse effects". Over-the-counter pain-relieving analgesics like Motrin and Advil are some of the most commonly used pharmaceutical compounds in the world used to treat aches, pains, fever, and arthritis.

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Clinically, this condition is called "compensated hypogonadism"-"hypogonadism" because the body probably isn't producing testosterone at the appropriate rate, and "compensated" because other hormones have kicked in and gotten testosterone levels to increase. Compensated hypogonadism typically develops in middle-aged males, yet the heavy dose induced the condition early on.

"However, this is now speculative". "We are concerned about it, particularly for healthy people who don't need to take these drugs".

The new study isn't the first to suggest that ibuprofen has downsides. It is worth noting that the study is actually a continuation of research looking into the effects of pain relievers on pregnant women.

While it is certain that the hormonal effects in the study participants who used ibuprofen for only a short time are reversible, as CBS reported, it's unknown whether this is also true after long-term ibuprofen use, study co-author Bernard Jegou, director of the Institute of Research in Environmental and Occupational Health in France, told CNN. "Based on these data, I personally would be very reluctant to take ibuprofen for longer than the 10 days normally indicated on the packet".

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